Ann‐Sofie Jemth

PARP is activated at stalled forks to mediate Mre11‐dependent replication restart and recombination

Helen E. Bryant, Eva Petermann, Niklas Schultz et al. · The EMBO Journal · 2009 · 589 citations · Full text

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 525 citations

Tumor Biology, Dntp Pool, Mth1 Inhibition +8

Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

K. Huber, E. Salah, Branka Radic-Sarikas et al. · Nature · 2014 · 387 citations · Full text

Medicinal Chemistry, Drug Targeting, Anticancer Strategy +9

Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Torkild Visnes, Armando Cázares‐Körner, Wenjing Hao et al. · Science · 2018 · 220 citations

A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family

Jordi Carreras‐Puigvert, Marinka Žitnik, Ann‐Sofie Jemth et al. · Nature Communications · 2017 · 163 citations · Full text