Nicholas C.K. Valerie

Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion

Sarah E. Golding, Elizabeth Rosenberg, Nicholas C.K. Valerie et al. · Molecular Cancer Therapeutics · 2009 · 389 citations · Full text

Medicine, Cancer Biology, Oncology +14

ATM Kinase Inhibition Preferentially Sensitizes p53-Mutant Glioma to Ionizing Radiation

Laura Biddlestone-Thorpe, Elizabeth Rosenberg, Jason M. Beckta et al. · Clinical Cancer Research · 2013 · 222 citations

Medicine, Oncology, Pharmacology +16

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies

Nikolas Herold, Sean G. Rudd, Linda Ljungblad et al. · Nature Medicine · 2017 · 142 citations

Medicine, Hematology, Pharmacology +10

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine

Nicholas C.K. Valerie, Anna Hagenkort, Brent D. G. Page et al. · Cancer Research · 2016 · 127 citations

Medicine, Oncology, Pharmacology +13

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Brent D. G. Page, Nicholas C.K. Valerie, Roni H. G. Wright et al. · Nature Communications · 2018 · 124 citations · Full text

Medicine, Molecular Biology, Oncology +16