Anna Hagenkort

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 525 citations

Tumor Biology, Dntp Pool, Mth1 Inhibition +8

Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities

Kumar Sanjiv, Anna Hagenkort, José Manuel Calderón‐Montaño et al. · Cell Reports · 2015 · 145 citations · Full text

Cancer-specific Synthetic Lethality, Oncogenic Agent, Medicine +12

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies

Nikolas Herold, Sean G. Rudd, Linda Ljungblad et al. · Nature Medicine · 2017 · 141 citations

Hematological Malignancy, Tumor Biology, Cytarabine Therapy +13

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine

Nicholas C.K. Valerie, Anna Hagenkort, Brent D. G. Page et al. · Cancer Research · 2016 · 127 citations

Nudt15 Ablation, Aldo-keto Reductase, Pharmacotherapy +18

Crystal structure, biochemical and cellular activities demonstrate separate functions of MTH1 and MTH2

Megan Carter, Ann‐Sofie Jemth, Anna Hagenkort et al. · Nature Communications · 2015 · 113 citations · Full text