Concepedia

Presenilin 2 Expression in Neuronal Cells: Induction during Differentiation of Embryonic Carcinoma Cells

Janetta G. Culvenor, Geneviève Evin, Melissa A. Cooney, Hady Wardan, Robyn A. Sharples, Fran Maher, Gullveig Reed, Anke Diehlmann, Andreas Weidemann, Konrad Beyreuther,

Experimental Cell Research · 2000 · 48 citations · 56 references

DOI

Concepts

References

56

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Bart De Strooper, Wim Annaert, Philippe Cupers et al. · Nature · 1999 · 2.1K citations

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Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

Michael S. Wolfe, Weiming Xia, Beth L. Ostaszewski et al. · Nature · 1999 · 1.9K citations

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

Andreas Weidemann, Gerhard König, Dirk Bunke et al. · Cell · 1989 · 1.2K citations

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Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo

Gopal Thinakaran, David Borchelt, Michael K. Lee et al. · Neuron · 1996 · 1K citations · Full text

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