Concepedia

Beth L. Ostaszewski

BL

Statistics

Publications

36

Citations

10.9K

H-Index

35

Active since

1992

Affiliations

Brigham and Women's Hospital(Current)

Harvard University

Athena Group (United States)

University of Tennessee at Knoxville

University of California San Diego

Beth L. Ostaszewski is an author at Brigham and Women's Hospital specializing in life sciences, amyloid formation, and amyloid beta peptides.

Publications per year

1992–2022

36

Publications

36

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity

Michael S. Wolfe, Weiming Xia, Beth L. Ostaszewski et al. · Nature · 1999 · 1.9K citations

, , +8

Amyloid β-peptide is produced by cultured cells during normal metabolism

Christian Haass, Michael G. Schlossmacher, Albert Y. Hung et al. · Nature · 1992 · 1.9K citations

, , +15

γ-Secretase is a membrane protein complex comprised of presenilin, nicastrin, aph-1, and pen-2

W. Taylor Kimberly, Matthew J. LaVoie, Beth L. Ostaszewski et al. · Proceedings of the National Academy of Sciences · 2003 · 758 citations

, , +16

Dopamine covalently modifies and functionally inactivates parkin

Matthew J. LaVoie, Beth L. Ostaszewski, Andreas Weihofen et al. · Nature Medicine · 2005 · 717 citations

, , +10

Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1

William P. Esler, W. Taylor Kimberly, Beth L. Ostaszewski et al. · Nature Cell Biology · 2000 · 520 citations

, , +13

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