Albert Y. Hung

Amyloid β-peptide is produced by cultured cells during normal metabolism

Christian Haass, Michael G. Schlossmacher, Albert Y. Hung et al. · Nature · 1992 · 1.9K citations

Amyloid β-Peptide, Protein Expression, Biochemistry +11

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations

Neurodegenerative Diseases, Alzheimer's Disease, β-Amyloid Precursor Protein +10

Targeting of cell-surface β-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments

Christian Haass, Edward H. Koo, Angela Mellon et al. · Nature · 1992 · 884 citations

Lysosomal Storage Disease, Protein Folding, Molecular Biology +6

beta-Amyloid peptide and a 3-kDa fragment are derived by distinct cellular mechanisms.

Christian Haass, Albert Y. Hung, Michael G. Schlossmacher et al. · Journal of Biological Chemistry · 1993 · 462 citations · Full text

Protein Secretion, Molecular Biology, Cytoskeleton +17

Activation of protein kinase C inhibits cellular production of the amyloid beta-protein.

Albert Y. Hung, Christian Haass, Roger M. Nitsch et al. · Journal of Biological Chemistry · 1993 · 402 citations · Full text

Amyloid Beta-protein, Alzheimer's Disease, Receptor Tyrosine Kinase +16