Edward H. Koo

Amyloid β-peptide is produced by cultured cells during normal metabolism

Christian Haass, Michael G. Schlossmacher, Albert Y. Hung et al. · Nature · 1992 · 1.9K citations

Amyloid β-Peptide, Protein Expression, Biochemistry +11

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Sascha Weggen, Jason L. Eriksen, Pritam Das et al. · Nature · 2001 · 1.4K citations

Inflammation, Molecular Pharmacology, Anti-inflammatory +7

Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells

Mason A. Israel, Shauna H. Yuan, Cédric Bardy et al. · Nature · 2012 · 1.2K citations

Neurodegenerative Diseases, Induced Pluripotent Stem Cell, Alzheimer's Disease +9

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

Alan H. Nagahara, David A. Merrill, Giovanni Coppola et al. · Nature Medicine · 2009 · 1K citations · Full text

Alzheimer's Disease, Health Sciences, Medicine +13

Evidence that production and release of amyloid beta-protein involves the endocytic pathway

Edward H. Koo, Sharon L. Squazzo · Journal of Biological Chemistry · 1994 · 987 citations · Full text

Protein Secretion, Alzheimer's Disease, Signal Transduction +12