Concepedia

Sascha Weggen

SW

71

Publications

7.5K

Citations

43

H-Index

1997

Active since

Affiliations

Heinrich Heine University Düsseldorf(Current)

Johannes Gutenberg University Mainz

University Medical Center of the Johannes Gutenberg University Mainz

University of California San Diego

University of Bonn

Sascha Weggen is an author at Heinrich Heine University Düsseldorf specializing in medicine, alzheimer's disease, and neurodegenerative diseases.

ORCID

Top concepts

Publications per year

1997–2023

71

Publications

71

A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity

Sascha Weggen, Jason L. Eriksen, Pritam Das et al. · Nature · 2001 · 1.4K citations

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NSAIDs and enantiomers of flurbiprofen target γ-secretase and lower Aβ42 in vivo

Jason L. Eriksen, Sarah A. Sagi, Tawnya E. Smith et al. · Journal of Clinical Investigation · 2003 · 617 citations · Full text

Endothelial LRP1 transports amyloid-β1–42 across the blood-brain barrier

Steffen E. Storck, Sabrina Meister, Julius Nahrath et al. · Journal of Clinical Investigation · 2015 · 439 citations · Full text

Evidence That Nonsteroidal Anti-inflammatory Drugs Decrease Amyloid β42 Production by Direct Modulation of γ-Secretase Activity

Sascha Weggen, Jason L. Eriksen, Sarah A. Sagi et al. · Journal of Biological Chemistry · 2003 · 287 citations · Full text

Diverse compounds mimic Alzheimer disease–causing mutations by augmenting Aβ42 production

Thomas Kukar, M. Paul Murphy, Jason L. Eriksen et al. · Nature Medicine · 2005 · 278 citations

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