Paul Säftig

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, Kotb Abdelmohsen, Akihisa Abe et al. · Autophagy · 2016 · 5.9K citations · Full text

Toll-like receptor 4–dependent contribution of the immune system to anticancer chemotherapy and radiotherapy

Lionel Apétoh, François Ghiringhelli, Antoine Tesnière et al. · Nature Medicine · 2007 · 2.9K citations

Inflammation, Toll-like Receptors, Cancer Immunosurveillance +12

A presenilin-1-dependent γ-secretase-like protease mediates release of Notch intracellular domain

Bart De Strooper, Wim Annaert, Philippe Cupers et al. · Nature · 1999 · 2.1K citations

Protein Secretion, Protein Function, Signal Transduction +8

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

Neurodegenerative Diseases, Alzheimer's Disease, Molecular Biology +9

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands

Umut Şahin, Gisela Weskamp, Kristine Kelly et al. · The Journal of Cell Biology · 2004 · 980 citations · Full text

Protein Function, Signal Transduction, Signaling Pathway +12