Konrad Beyreuther

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

Jie Kang, Hans-Georg Lemaire, Axel Unterbeck et al. · Nature · 1987 · 4.6K citations

Life Sciences, Molecular Biology, Neuroscience +14

Treatment with a Copper-Zinc Chelator Markedly and Rapidly Inhibits β-Amyloid Accumulation in Alzheimer's Disease Transgenic Mice

Robert A. Cherny, Craig Atwood, Michel Xilinas et al. · Neuron · 2001 · 1.5K citations · Full text

Life Sciences, Neuroscience, Pharmacology +13

Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

Andreas Weidemann, Gerhard König, Dirk Bunke et al. · Cell · 1989 · 1.2K citations

Life Sciences, Biochemistry, Molecular Biology +12

Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

Mikael Simons, Patrick Keller, Bart De Strooper et al. · Proceedings of the National Academy of Sciences · 1998 · 1.2K citations

Life Sciences, Biochemistry, Neuroscience +17

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 <i>in vitro</i> and <i>in vivo</i>

Mikael Simons, Christine Bergmann, Mark Stroick et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15