Patrick Keller

Alzheimer's disease β-amyloid peptides are released in association with exosomes

Lawrence Rajendran, Masanori Honsho, Tobias Zahn et al. · Proceedings of the National Academy of Sciences · 2006 · 1.3K citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

Mikael Simons, Patrick Keller, Bart De Strooper et al. · Proceedings of the National Academy of Sciences · 1998 · 1.2K citations

Life Sciences, Biochemistry, Neuroscience +17

Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts

Robert Ehehalt, Patrick Keller, Christian Haass et al. · The Journal of Cell Biology · 2003 · 1.1K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 <i>in vitro</i> and <i>in vivo</i>

Mikael Simons, Christine Bergmann, Mark Stroick et al. · Proceedings of the National Academy of Sciences · 2001 · 1.1K citations · Full text

Life Sciences, Neuroscience, Pharmacology +15

Sphingolipid–Cholesterol Rafts Diffuse as Small Entities in the Plasma Membrane of Mammalian Cells

Arnd Pralle, Patrick Keller, Ernst‐Ludwig Florin et al. · The Journal of Cell Biology · 2000 · 982 citations · Full text

Life Sciences, Biophysics, Cell Biology +17