Hypocholesterolemic Effect of Peanut Skin and Its Fractions: A Case Record of Rats Fed on a High-Cholesterol Diet

Akiko Shimizu‐Ibuka, Haruhide Udagawa, Kazuo Kobayashi, Kiyoshi Mura, Chiyoko Tokue, Toshichika Takita, Soichi Arai

Bioscience Biotechnology and Biochemistry · 2009 · 27 citations · 8 references

DOIFull text

Open access

Concepts

Abstract

Peanut skin (PS) is characterized by almost exclusively consisting of polyphenols and fiber. We fractionated PS into a water-soluble fraction (WSF) and water-insoluble fraction (WIF), and further fractionated WSF into a soluble dietary fiber fraction (DF) and dietary fiber-free, water-soluble fraction (DFF-WSF). Male Sprague-Dawley rats were fed on high-cholesterol diets supplemented with PS and its fractions. PS, WSF, and DFF-WSF decreased the serum lipid and cholesterol levels and increased those in feces. This effect was probably due to the polyphenols that inhibited intestinal cholesterol absorption.

References

8