Concepedia

Difluoroethylamines as an amide isostere in inhibitors of cathepsin K

Élise Isabel, Christophe Mellon, Michael J. Boyd, Nathalie Chauret, Denis Deschênes, Sylvie Desmarais, Jean‐Pierre Falgueyret, Jacques Yves Gauthier, Karine Khougaz, Cheuk K. Lau,

Bioorganic & Medicinal Chemistry Letters · 2010 · 111 citations · 20 references

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20

Peptidomimetics—Tailored Enzyme Inhibitors

Joachim Gante · Angewandte Chemie International Edition in English · 1994 · 817 citations

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The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 473 citations · Full text

, , +10

A novel chromium trioxide catalyzed oxidation of primary alcohols to the carboxylic acids

Mangzhu Zhao, Jing Li, Zhiguo J. Song et al. · Tetrahedron Letters · 1998 · 221 citations

, , +14

Trifluoroethylamines as amide isosteres in inhibitors of cathepsin K

W. Cameron Black, Christopher I. Bayly, Dana Davis et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 140 citations

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Novel, Nonpeptidic Cyanamides as Potent and Reversible Inhibitors of Human Cathepsins K and L

Jean‐Pierre Falgueyret, Renata M. Oballa, Osamu Okamoto et al. · Journal of Medicinal Chemistry · 2000 · 128 citations · Full text

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