Concepedia

Cathepsin Activity

Cathepsin Activity is a biochemical process characterized by the proteolytic degradation of muscle proteins mediated by lysosomal cysteine cathepsins during postmortem muscle conversion, distinguishing it from other proteolytic systems through its pH-dependent activation and specific substrate cleavage patterns in the context of meat tenderization.

8.9K

Publications

524.4K

Citations

36K

Authors

5K

Institutions

Publications per year

2017–2026

1.4K

Parents

Publications

8.9K

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Xiuyuan Ou, Yan Liu, Xiaobo Lei et al. · Nature Communications · 2020 · 3.4K citations · Full text

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THE ESTIMATION OF PEPSIN, TRYPSIN, PAPAIN, AND CATHEPSIN WITH HEMOGLOBIN

M. L. Anson · The Journal of General Physiology · 1938 · 3.3K citations · Full text

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Cysteine cathepsins: From structure, function and regulation to new frontiers

Vito Türk, Veronika Stoka, Olga Vasiljeva et al. · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics · 2011 · 1.4K citations · Full text

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Evidence that TMPRSS2 Activates the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Membrane Fusion and Reduces Viral Control by the Humoral Immune Response

Ilona Glowacka, Stephanie Bertram, Marcel A. Müller et al. · Journal of Virology · 2011 · 1.2K citations · Full text

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Activation of the SARS coronavirus spike protein via sequential proteolytic cleavage at two distinct sites

Sandrine Belouzard, Victor C. Chu, Gary R. Whittaker · Proceedings of the National Academy of Sciences · 2009 · 1.2K citations · Full text

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1–5 of 8.9K

Authors

36K

  1. DB
    Dieter Brömme

    University of British Columbia, Canada

    108 publications · 9.4K citations

    53

    h-index

  2. VT
    Vito Türk

    Jožef Stefan Institute, Slovenia

    114 publications · 9.4K citations

    53

    h-index

  3. BF
    Bonnie F. Sloane

    Wayne State University, United States

    89 publications · 7.9K citations

    52

    h-index

  4. CP
    Christoph Peters

    University of Freiburg, Germany

    74 publications · 9K citations

    51

    h-index

  5. TR
    Thomas Reinheckel

    University of Freiburg, Germany

    86 publications · 7.9K citations

    49

    h-index

1–5 of 36K

Institutions

5K

  1. Harvard University

    Cambridge, United States

    89 h-index

    799 publications

    114.1K citations

  2. Inserm

    Paris, France

    70 h-index

    1.1K publications

    70.8K citations

  3. Jožef Stefan Institute

    Ljubljana, Slovenia

    67 h-index

    638 publications

    49.5K citations

  4. University of California, San Francisco

    San Francisco, United States

    60 h-index

    444 publications

    51.4K citations

  5. University of Freiburg

    Freiburg im Breisgau, Germany

    53 h-index

    350 publications

    31.9K citations

  6. Brigham and Women's Hospital

    Boston, United States

    53 h-index

    416 publications

    60.1K citations

  7. Wayne State University

    Detroit, United States

    53 h-index

    286 publications

    27K citations

  8. Icahn School of Medicine at Mount Sinai

    New York, United States

    50 h-index

    275 publications

    25.8K citations

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Venues

  1. Journal of Biological Chemistry

    JBC · 418 publications · 42.3K citations

    115

    h-index

  2. Biochemical Journal

    BJ · 205 publications · 17.8K citations

    74

    h-index

  3. PubMed

    Repository · 454 publications · 21.4K citations

    71

    h-index

  4. The Journal of Immunology

    JI · 114 publications · 8.9K citations

    65

    h-index

  5. FEBS Letters

    177 publications · 10.5K citations

    59

    h-index

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