Élise Isabel

Difluoroethylamines as an amide isostere in inhibitors of cathepsin K

Élise Isabel, Christophe Mellon, Michael J. Boyd et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 111 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Science +10

Reversible Cysteine Protease Inhibitors Show Promise for a Chagas Disease Cure

Momar Ndao, Christian Beaulieu, W. Cameron Black et al. · Antimicrobial Agents and Chemotherapy · 2013 · 103 citations · Full text

Antiparasitic Agent, Immunology, Pathology +21

Identification of potent and reversible cruzipain inhibitors for the treatment of Chagas disease

Christian Beaulieu, Élise Isabel, Angélique Fortier et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 70 citations · Full text

Medicinal Chemistry, Reversible Cruzipain Inhibitors, Medicine +5

Preparation, Solid-State Structure, and Synthetic Applications of Isolable and Storable Haloalkylzinc Reagents

André B. Charette, Jean-François Marcoux, Carmela Molinaro et al. · Journal of the American Chemical Society · 2000 · 68 citations

Solid-state Structure, Chemical Engineering, Engineering +12

Discovery of potent and liver-targeted stearoyl-CoA desaturase (SCD) inhibitors in a bispyrrolidine series

Nicolas Lachance, Yves Gareau, Sébastien Guiral et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 28 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Liver-targeted Stearoyl-coa Desaturase +12