Yves Gareau

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

Life Sciences, Cell Biology, Molecular Biology +13

Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

Iman Fares, Jalila Chagraoui, Yves Gareau et al. · Science · 2014 · 566 citations

Medicine, Medicinal Chemistry, Pharmacology +16

The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs

Mark Abramovitz, Mohammed Adam, Yves Boie et al. · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids · 2000 · 557 citations · Full text

Life Sciences, Biochemistry, Pharmacology +10

The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis

J. Rotonda, Donald W. Nicholson, Kimberly M. Fazil et al. · Nature Structural Biology · 1996 · 433 citations

Life Sciences, Biochemistry, Molecular Biology +14

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

Irène Baccelli, Yves Gareau, Bernhard Lehnertz et al. · Cancer Cell · 2019 · 262 citations · Full text

Medicine, Oncology, Pharmacology +12