Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

Iman Fares, Jalila Chagraoui, Yves Gareau, +19

Science

Cell TherapyImmunologyBlood CellStem Cell MobilizationStem Cell Transplantation +16

Human endothelial cells derived from circulating progenitors display specific functional properties compared with mature vessel wall endothelial cells

Heidi Bompais, Jalila Chagraoui, Xavier Canron, +8

Blood

A key role for <i>EZH2</i> and associated genes in mouse and human adult T-cell acute leukemia

Camille Simon, Jalila Chagraoui, Jana Krošl, +13

Genes & Development

EPCR expression marks UM171-expanded CD34+ cord blood stem cells

Iman Fares, Jalila Chagraoui, Bernhard Lehnertz, +6

Blood

Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1–2 safety and feasibility study

Sandra Cohen, Jean Roy, Silvy Lachance, +25

The Lancet Haematology

Regenerative MedicineCell TherapyTransplantationMarrow TransplantationStem Cell Transplantation +9

Fetal liver stroma consists of cells in epithelial-to-mesenchymal transition

Jalila Chagraoui, Adeline Lepage-Noll, A Anjo, +2

Blood

A Functional Screen to Identify Novel Effectors of Hematopoietic Stem Cell Activity

Éric Deneault, Sonia Cellot, Amélie Faubert, +7

Cell

MedicineStem Cell MobilizationHematologyIdentify Novel EffectorsStem Cell Research +9

A role for GPx3 in activity of normal and leukemia stem cells

Olivier Hérault, Kristin J. Hope, Éric Deneault, +8

The Journal of Experimental Medicine

Hematological MalignancyGpx3 ShrnaLineage PlasticityDevelopmental BiologyGpx3 Promoter Region +12

Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2

Stephen B. Ting, Éric Deneault, Kristin J. Hope, +11

Blood

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex

Jalila Chagraoui, Simon Girard, Jean-François Spinella, +12

Cell stem cell

Clr3-kbtbd4 ComplexChromatinChromatin RemodelingMedicineGenetics +8