Suv39h-Mediated Histone H3 Lysine 9 Methylation Directs DNA Methylation to Major Satellite Repeats at Pericentric Heterochromatin

Bernhard Lehnertz, Yoshihide Ueda, Alwin A.H.A. Derijck, +7

Current Biology

Histone ModificationsChromatinChromatin StructureChromatin RemodelingNatural Sciences +13

Mubritinib Targets the Electron Transport Chain Complex I and Reveals the Landscape of OXPHOS Dependency in Acute Myeloid Leukemia

Irène Baccelli, Yves Gareau, Bernhard Lehnertz, +26

Cancer Cell

Hematological MalignancyBiochemistryNatural SciencesAcute Myeloid LeukemiaOxphos Dependency +7

EPCR expression marks UM171-expanded CD34+ cord blood stem cells

Iman Fares, Jalila Chagraoui, Bernhard Lehnertz, +6

Blood

Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1–2 safety and feasibility study

Sandra Cohen, Jean Roy, Silvy Lachance, +25

The Lancet Haematology

Regenerative MedicineCell TherapyTransplantationMarrow TransplantationStem Cell Transplantation +9

Control of the Hippo Pathway by Set7-Dependent Methylation of Yap

Menno J. Oudhoff, Spencer A. Freeman, Amber L. Couzens, +13

Developmental Cell

The methyltransferase G9a regulates HoxA9-dependent transcription in AML

Bernhard Lehnertz, Caroline Pabst, Le Su, +14

Genes & Development

Histone ModificationsChromatin ModulatorsMixed-phenotype Acute LeukemiaGeneticsDna Methylation +18

Activating and inhibitory functions for the histone lysine methyltransferase G9a in T helper cell differentiation and function

Bernhard Lehnertz, Jeffrey P. Northrop, Frann Antignano, +5

The Journal of Experimental Medicine

Histone ModificationsHistone Lysine MethylationLymphocyte DevelopmentEpigenetic ChangeGenetics +19

Lysine methyltransferase G9a is required for de novo DNA methylation and the establishment, but not the maintenance, of proviral silencing

Danny Leung, Kevin Dong, Irina A. Maksakova, +9

Proceedings of the National Academy of Sciences

Genetic characterization of ABT-199 sensitivity in human AML

Richard Bisaillon, Céline Moison, Clarisse Thiollier, +16

Leukemia

Human AmlAllelic VariantMedicineGeneticsHuman Polymorphism +4

<i>HLF</i> expression defines the human hematopoietic stem cell state

Bernhard Lehnertz, Jalila Chagraoui, Tara MacRae, +7

Blood