Nathalie Chauret

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 467 citations · Full text

Molecular Pharmacology, Pharmaceutical Chemistry, Biochemistry +11

Effect of common organic solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes.

Nathalie Chauret, Annick Gauthier, Deborah A. Nicoll‐Griffith · PubMed · 1998 · 309 citations

Metabolomic Profiling, Toxicological Mechanism, Medicinal Chemistry +19

In vitro comparison of cytochrome P450-mediated metabolic activities in human, dog, cat, and horse.

Nathalie Chauret, Annick Gauthier, Jean‐Frédéric Martin et al. · PubMed · 1997 · 185 citations

Metabolomic Profiling, Laboratory Animal Study, Pharmacological Study +19

Discovery of a Potent and Selective Prostaglandin D₂ Receptor Antagonist, [(3<i>R</i>)-4-(4-Chloro- benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[<i>b</i>]indol-3-yl]-acetic Acid (MK-0524)

Claudio F. Sturino, Gary P. O’Neill, Nicolas Lachance et al. · Journal of Medicinal Chemistry · 2007 · 170 citations · Full text

A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds

Renata M. Oballa, Jean‐François Truchon, Christopher I. Bayly et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 147 citations

Chemical Engineering, Engineering, Applicable Method +7