Deborah A. Nicoll‐Griffith

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

Jacques Yves Gauthier, Nathalie Chauret, Wanda Cromlish et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 467 citations · Full text

Molecular Pharmacology, Pharmaceutical Chemistry, Biochemistry +11

Effect of common organic solvents on in vitro cytochrome P450-mediated metabolic activities in human liver microsomes.

Nathalie Chauret, Annick Gauthier, Deborah A. Nicoll‐Griffith · PubMed · 1998 · 309 citations

Metabolomic Profiling, Toxicological Mechanism, Medicinal Chemistry +19

Arachidonyl trifluoromethyl ketone, a potent inhibitor of 85-kDa phospholipase A2, blocks production of arachidonate and 12-hydroxyeicosatetraenoic acid by calcium ionophore-challenged platelets.

Denis Riendeau, Jocelyne Guay, P K Weech et al. · Journal of Biological Chemistry · 1994 · 258 citations · Full text

MS ^E with mass defect filtering for <i>in vitro</i> and <i>in vivo</i> metabolite identification

Kevin P. Bateman, José Castro‐Perez, Mark Wrona et al. · Rapid Communications in Mass Spectrometry · 2007 · 254 citations

In vitro comparison of cytochrome P450-mediated metabolic activities in human, dog, cat, and horse.

Nathalie Chauret, Annick Gauthier, Jean‐Frédéric Martin et al. · PubMed · 1997 · 185 citations

Metabolomic Profiling, Laboratory Animal Study, Pharmacological Study +19