Cheuk K. Lau

Reductive deoxygenation of aryl aldehydes and ketones and benzylic, allylic, and tertiary alcohols by zinc iodide-sodium cyanoborohydride

Cheuk K. Lau, Claude Dufresne, Patrice C. Bélanger et al. · The Journal of Organic Chemistry · 1986 · 114 citations

Reductive Deoxygenation, Chemical Engineering, Engineering +13

Difluoroethylamines as an amide isostere in inhibitors of cathepsin K

Élise Isabel, Christophe Mellon, Michael J. Boyd et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 111 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Pharmaceutical Science +10

From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors

W. Cameron Black, Christopher I. Bayly, Michel Belley et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 107 citations

Medicinal Chemistry, Anti-inflammatory, Selective Cox-2 Inhibitor +11

The Structural Basis for the Selectivity of Benzotriazole Inhibitors of PTP1B

Giovanna Scapin, Sangita B. Patel, Joseph W. Becker et al. · Biochemistry · 2003 · 104 citations · Full text

Drug Target, Selective Ptp1b Inhibitors, Molecular Biology +19

The C3a receptor antagonist SB 290157 has agonist activity

Marie‐Claude Mathieu, Nicole Sawyer, Gillian Greig et al. · Immunology Letters · 2005 · 92 citations

Functional Selectivity, Medicine, Agonist Activity +4