The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs

Mark Abramovitz, Mohammed Adam, Yves Boie, +16

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Related AnalogsSignal TransductionBiochemistryFunctional SelectivityMedicine +11

Pharmacology of L-660,711 (MK-571): a novel potent and selective leukotriene D₄ receptor antagonist

Thomas R. Jones, Robert Zamboni, Michel Belley, +14

Canadian Journal of Physiology and Pharmacology

Pharmacology of montelukast sodium (Singulair™), a potent and selective leukotriene D₄receptor antagonist

Thomas R. Jones, Marc Labelle, Michel Belley, +18

Canadian Journal of Physiology and Pharmacology

InflammationMolecular PharmacologyAnti-inflammatoryBiochemistryMedicine +12

γ-Aminobutyric Acid Type B Receptors with Specific Heterodimer Composition and Postsynaptic Actions in Hippocampal Neurons Are Targets of Anticonvulsant Gabapentin Action

Gordon Ng, Sandrine S. Bertrand, Richard Sullivan, +13

Molecular Pharmacology

From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors

W. Cameron Black, Christopher I. Bayly, Michel Belley, +19

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryAnti-inflammatorySelective Cox-2 InhibitorBiochemistryMedicine +9

Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction

Marc Labelle, Michel Belley, Yves Gareau, +20

Bioorganic & Medicinal Chemistry Letters

InflammationAnti-inflammatoryFunctional SelectivityMedicineImmunology +5

Comparison of the Antinociceptive Profiles of Gabapentin and 3-Methylgabapentin in Rat Models of Acute and Persistent Pain: Implications for Mechanism of Action

M.O. Urban, Ke Ren, Ki‐Tae Park, +7

Journal of Pharmacology and Experimental Therapeutics

.alpha.-(Arylsulfonamido)borneols as auxiliaries in asymmetric synthesis: an efficient and highly stereoselective method for the reduction of .alpha.-keto esters

Yi Xiang, Ken Snow, Michel Belley

The Journal of Organic Chemistry

EngineeringBiochemistryNatural Sciences.Alpha.-keto EstersStereoselective Method +10

Discovery of [(3-bromo-7-cyano-2-naphthyl)(difluoro)methyl]phosphonic acid, a potent and orally active small molecule PTP1B inhibitor

Yongxin Han, Michel Belley, Christopher I. Bayly, +12

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryDrug TargetBiochemistryNatural SciencesMedicine +8

The identification of 4,7-disubstituted naphthoic acid derivatives as UDP-competitive antagonists of P2Y14

Jacques Yves Gauthier, Michel Belley, Denis Deschênes, +20

Bioorganic & Medicinal Chemistry Letters

Pharmaceutical ScienceDerivative (Chemistry)BiochemistryNatural SciencesMedicine +7