Concepedia

Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes

Sébastien S. Hébert, Lutgarde Serneels, Alexandra Tolia, Katleen Craessaerts, Carmen Derks, Mikhail A Filippov, Ulrike Müller, Bart De Strooper

EMBO Reports · 2006 · 187 citations · 21 references

DOI

Concepts

References

21

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

, , +15

Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat et al. · Nature · 1995 · 1.4K citations

, , +9

Exchange of N-CoR Corepressor and Tip60 Coactivator Complexes Links Gene Expression by NF-κB and β-Amyloid Precursor Protein

Sung Hee Baek, Kenneth A. Ohgi, David W. Rose et al. · Cell · 2002 · 554 citations · Full text

, , +11

The Intracellular Domain of the β-Amyloid Precursor Protein Is Stabilized by Fe65 and Translocates to the Nucleus in a Notch-like Manner

W. Taylor Kimberly, Jessica B. Zheng, Suzanne Y. Guénette et al. · Journal of Biological Chemistry · 2001 · 437 citations · Full text

, , +16

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor

Ruth C. von Rotz, Bernhard M. Kohli, Jérôme Bosset et al. · Journal of Cell Science · 2004 · 341 citations · Full text

, , +16