Concepedia

Amyloid Fibrillogenesis

Amyloid Fibrillogenesis is a biochemical process defined as the pathogenic self-assembly of misfolded proteins into highly ordered, insoluble fibrillar aggregates characterized by a cross-β sheet quaternary structure, distinct from other protein aggregation mechanisms by its specific structural morphology and resistance to degradation.

3.7K

Publications

318.3K

Citations

13.9K

Authors

2.7K

Institutions

Publications per year

2017–2026

845

Parents

Publications

3.7K

Consort 2010 statement: extension to cluster randomised trials

Marion Campbell, Gilda Piaggio, Diana R Elbourne et al. · BMJ · 2012 · 3.6K citations · Full text

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Diffusible, nonfibrillar ligands derived from Aβ <sub>1–42</sub> are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

, , +17

3D structure of Alzheimer's amyloid-β(1–42) fibrils

Thorsten Lührs, Christiane Ritter, Marc Adrian et al. · Proceedings of the National Academy of Sciences · 2005 · 2K citations · Full text

, , +17

Amyloid β-peptide is produced by cultured cells during normal metabolism

Christian Haass, Michael G. Schlossmacher, Albert Y. Hung et al. · Nature · 1992 · 1.9K citations

, , +15

Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

Bart De Strooper, Paul Säftig, Katleen Craessaerts et al. · Nature · 1998 · 1.8K citations

, , +15

1–5 of 3.7K

Authors

13.9K

  1. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    63 publications · 11.5K citations

    50

    h-index

  2. PW
    Per Westermark

    Uppsala University, Sweden

    67 publications · 8.3K citations

    41

    h-index

  3. HN
    Hironobu Naiki

    University of Fukui, Japan

    58 publications · 6.6K citations

    39

    h-index

  4. YG
    Yuji Goto

    The University of Osaka, Japan

    54 publications · 3.7K citations

    36

    h-index

  5. MF
    Marcus Fändrich

    Universität Ulm, Germany

    39 publications · 4.3K citations

    30

    h-index

1–5 of 13.9K

Institutions

2.7K

  1. Harvard University

    Cambridge, United States

    57 h-index

    293 publications

    95.5K citations

  2. University of Cambridge

    Cambridge, United Kingdom

    56 h-index

    309 publications

    44.3K citations

  3. National Institutes of Health

    Bethesda, United States

    47 h-index

    217 publications

    34.7K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    43 h-index

    342 publications

    18.2K citations

  5. Brigham and Women's Hospital

    Boston, United States

    41 h-index

    152 publications

    64.4K citations

  6. New York University

    New York, United States

    41 h-index

    210 publications

    29K citations

  7. The University of Osaka

    Osaka, Japan

    39 h-index

    309 publications

    19.5K citations

  8. University of Fukui

    Fukui-shi, Japan

    39 h-index

    145 publications

    12.4K citations

1–8 of 2.7K

Venues

  1. Journal of Biological Chemistry

    JBC · 238 publications · 29.1K citations

    94

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 123 publications · 33.2K citations

    87

    h-index

  3. Journal of Molecular Biology

    JMB · 141 publications · 14K citations

    72

    h-index

  4. Biochemistry

    159 publications · 16.9K citations

    67

    h-index

  5. Biochemical and Biophysical Research Communications

    BBRC · 103 publications · 8.7K citations

    48

    h-index

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