Concepedia

Mammalian Target of Rapamycin Complex 1 Activation Is Required for the Stimulation of Human Skeletal Muscle Protein Synthesis by Essential Amino Acids1–3

Jared M. Dickinson, Christopher S. Fry, Micah J. Drummond, David M. Gundermann, Dillon K. Walker, Erin L. Glynn, Kyle L. Timmerman, Shaheen Dhanani, Elena Volpi, Blake B. Rasmussen

Journal of Nutrition · 2011 · 289 citations · 38 references

DOI

Concepts

References

38

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

Yasemin Sancak, Timothy R. Peterson, Yoav D. Shaul et al. · Science · 2008 · 2.8K citations

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Sue C. Bodine, Trevor N. Stitt, Michael Gonzalez et al. · Nature Cell Biology · 2001 · 2.7K citations

, , +14

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

Carson C. Thoreen, Seong A. Kang, Jae Won Chang et al. · Journal of Biological Chemistry · 2009 · 1.8K citations · Full text

, , +14

Regulation of TORC1 by Rag GTPases in nutrient response

Eunjung Kim, Pankuri Goraksha-Hicks, Li Li et al. · Nature Cell Biology · 2008 · 1.3K citations · Full text

, , +12

Anabolic signaling deficits underlie amino acid resistance of wasting, aging muscle

Daniel J. Cuthbertson, Kenneth Smith, John Babraj et al. · The FASEB Journal · 2004 · 1.2K citations

, , +17