Identification of Ubiquitin Ligases Required for Skeletal Muscle Atrophy

Sue C. Bodine, Esther Latres, Susanne Baumhueter, +13

Science

Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

Sue C. Bodine, Trevor N. Stitt, Michael Gonzalez, +8

Nature Cell Biology

Skeletal Muscle HypertrophyMolecular PhysiologyMuscle InjuryMuscle FunctionSkeletal Muscle +8

The IGF-1/PI3K/Akt Pathway Prevents Expression of Muscle Atrophy-Induced Ubiquitin Ligases by Inhibiting FOXO Transcription Factors

Trevor N. Stitt, Doreen Drujan, Brian Clarke, +6

Molecular Cell

Muscle FunctionSignaling PathwayCell RegulationSkeletal MuscleMedicine +6

Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways

Christian Rommel, Sue C. Bodine, Brian Clarke, +5

Nature Cell Biology

Molecular PhysiologySignal TransductionSignaling PathwayGrowth HormoneSkeletal Muscle +6

trkB encodes a functional receptor for brain-derived neurotrophic factor and neurotrophin-3 but not nerve growth factor

Stephen P. Squinto, Trevor N. Stitt, Thomas H. Aldrich, +9

Cell

Brain-derived Neurotrophic FactorSynaptic PlasticitySignal TransductionNerve Growth FactorNeurotransmission +8

The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases

Trevor N. Stitt, Greg Conn, Martin Goret, +18

Cell

Agrin Acts via a MuSK Receptor Complex

David J. Glass, David C. Bowen, Trevor N. Stitt, +11

Cell

The E3 Ligase MuRF1 Degrades Myosin Heavy Chain Protein in Dexamethasone-Treated Skeletal Muscle

Brian Clarke, Doreen Drujan, Monte S. Willis, +8

Cell Metabolism

Muscle PhysiologyMuscle FunctionMolecular PhysiologyMuscle InjurySkeletal Muscle +10

Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells

Nancy Y. Ip, Trevor N. Stitt, Peter Tapley, +6

Neuron

Synaptic TransmissionNonneuronal CellsNeuropeptide ReceptorTrk ReceptorsNeurotransmission +7

Conditional Activation of Akt in Adult Skeletal Muscle Induces Rapid Hypertrophy

Ka‐Man Venus Lai, Michael Gonzalez, William Poueymirou, +7

Molecular and Cellular Biology

Skeletal Muscle HypertrophySignal TransductionMolecular PhysiologyKinesiologyMuscle Function +13