Jae Won Chang

Systematic identification of genomic markers of drug sensitivity in cancer cells

Mathew J. Garnett, Elena J. Edelman, Sonja J. Heidorn et al. · Nature · 2012 · 2.5K citations · Full text

Systematic Identification, Genomic Markers, Engineering +12

An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1

Carson C. Thoreen, Seong A. Kang, Jae Won Chang et al. · Journal of Biological Chemistry · 2009 · 1.8K citations · Full text

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1<i>H</i>)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

Qingsong Liu, Jae Won Chang, Jinhua Wang et al. · Journal of Medicinal Chemistry · 2010 · 251 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +20

Nonthermal plasma induces head and neck cancer cell death: the potential involvement of mitogen-activated protein kinase-dependent mitochondrial reactive oxygen species

Sung-Ung Kang, JH Cho, Jae Won Chang et al. · Cell Death and Disease · 2014 · 207 citations · Full text

Tissue‐Engineered Tracheal Reconstruction Using Three‐Dimensionally Printed Artificial Tracheal Graft: Preliminary Report

Jae Won Chang, Su A Park, Ju‐Kyeong Park et al. · Artificial Organs · 2014 · 150 citations · Full text