Jinhua Wang

A Landscape of Pharmacogenomic Interactions in Cancer

Francesco Iorio, Theo Knijnenburg, Daniël J. Vis et al. · Cell · 2016 · 2.2K citations · Full text

Tumor Biology, Oncology, Tumor Heterogeneity +13

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1<i>H</i>)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

Qingsong Liu, Jae Won Chang, Jinhua Wang et al. · Journal of Medicinal Chemistry · 2010 · 251 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +20

Discovery of 9-(6-Aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[<i>h</i>][1,6]naphthyridin-2(1<i>H</i>)-one (Torin2) as a Potent, Selective, and Orally Available Mammalian Target of Rapamycin (mTOR) Inhibitor for Treatment of Cancer

Qingsong Liu, Jinhua Wang, Seong A. Kang et al. · Journal of Medicinal Chemistry · 2011 · 212 citations · Full text

Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Qingsong Liu, Chunxiao Xu, Sivapriya Kirubakaran et al. · Cancer Research · 2013 · 207 citations · Full text

mTOR mediated anti-cancer drug discovery

Qingsong Liu, Carson C. Thoreen, Jinhua Wang et al. · Drug Discovery Today Therapeutic Strategies · 2009 · 171 citations · Full text

Medicine, Anti-cancer Drug Discovery, Anti-cancer Agent +4