Concepedia

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

Friedrich Reinhard, Dirk Eberhard, Thilo Werner, Holger Franken, Dorothee Childs, Carola Doce, Maria Fälth Savitski, Mikhail M. Savitski, Gerard Drewes

Nature Methods · 2015 · 319 citations · 26 references

DOI

Concepts

References

26

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko et al. · Science · 2013 · 2.2K citations

, , +17

The cellular thermal shift assay for evaluating drug target interactions in cells

Rozbeh Jafari, Helena Almqvist, Hanna Axelsson et al. · Nature Protocols · 2014 · 1.5K citations

, , +13

Protter: interactive protein feature visualization and integration with experimental proteomic data

Ulrich Omasits, Christian H. Ahrens, S. Müller et al. · Bioinformatics · 2013 · 1.4K citations · Full text

, , +17

Tracking cancer drugs in living cells by thermal profiling of the proteome

Mikhail M. Savitski, Friedrich Reinhard, Holger Franken et al. · Science · 2014 · 1.2K citations

, , +17

Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

Marcus Bantscheff, Dirk Eberhard, Yann Abraham et al. · Nature Biotechnology · 2007 · 1K citations

, , +14