Carola Doce

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

Holger Franken, Toby Mathieson, Dorothee Childs et al. · Nature Protocols · 2015 · 682 citations

Drug Target, Thermal Proteome Profiling, Biochemistry +11

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

Friedrich Reinhard, Dirk Eberhard, Thilo Werner et al. · Nature Methods · 2015 · 307 citations

Proteomic Technology, Proteinlipid Interaction, Protein Function +9

Measuring and Managing Ratio Compression for Accurate iTRAQ/TMT Quantification

Mikhail M. Savitski, Toby Mathieson, Nico Zinn et al. · Journal of Proteome Research · 2013 · 286 citations · Full text

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat

Isabelle Becher, Thilo Werner, Carola Doce et al. · Nature Chemical Biology · 2016 · 250 citations

Biosynthesis, Engineering, Biochemistry +9

High-Resolution Enabled TMT 8-plexing

Thilo Werner, Isabelle Becher, Gavain M.A. Sweetman et al. · Analytical Chemistry · 2012 · 199 citations

High Resolution, Engineering, Molecular Biology +18