Friedrich Reinhard

Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

Holger Franken, Toby Mathieson, Dorothee Childs et al. · Nature Protocols · 2015 · 682 citations

Drug Target, Thermal Proteome Profiling, Biochemistry +11

A Novel ε-Cleavage within the Transmembrane Domain of the Alzheimer Amyloid Precursor Protein Demonstrates Homology with Notch Processing

Andreas Weidemann, Simone Eggert, Friedrich Reinhard et al. · Biochemistry · 2002 · 349 citations

Neurodegenerative Diseases, Protein Secretion, Alzheimer's Disease +15

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

Friedrich Reinhard, Dirk Eberhard, Thilo Werner et al. · Nature Methods · 2015 · 307 citations

Proteomic Technology, Proteinlipid Interaction, Protein Function +9

Proteolytic Processing of the Alzheimer's Disease Amyloid Precursor Protein within Its Cytoplasmic Domain by Caspase-like Proteases

Andreas Weidemann, Krzysztof Paliga, Ulrike Dürrwang et al. · Journal of Biological Chemistry · 1999 · 169 citations · Full text

Combining Human Computing and Machine Learning to Make Sense of Big (Aerial) Data for Disaster Response

Ferda Ofli, Patrick Meier, Muhammad Imran et al. · Big Data · 2016 · 158 citations

Artificial Intelligence, Data Annotation, Engineering +22