Hanna Axelsson

The cellular thermal shift assay for evaluating drug target interactions in cells

Rozbeh Jafari, Helena Almqvist, Hanna Axelsson et al. · Nature Protocols · 2014 · 1.4K citations

Drug Target, Drug Targeting, Medicine +9

MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool

Helge Gad, Tobias Koolmeister, Ann‐Sofie Jemth et al. · Nature · 2014 · 525 citations

Tumor Biology, Dntp Pool, Mth1 Inhibition +8

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Helena Almqvist, Hanna Axelsson, Rozbeh Jafari et al. · Nature Communications · 2016 · 162 citations · Full text

Targeting SAMHD1 with the Vpx protein to improve cytarabine therapy for hematological malignancies

Nikolas Herold, Sean G. Rudd, Linda Ljungblad et al. · Nature Medicine · 2017 · 141 citations

Hematological Malignancy, Tumor Biology, Cytarabine Therapy +13

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Brent D. G. Page, Nicholas C.K. Valerie, Roni H. G. Wright et al. · Nature Communications · 2018 · 121 citations · Full text