Helena Almqvist

The cellular thermal shift assay for evaluating drug target interactions in cells

Rozbeh Jafari, Helena Almqvist, Hanna Axelsson et al. · Nature Protocols · 2014 · 1.5K citations

Medicine, Cell Biology, Pharmacology +13

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Helena Almqvist, Hanna Axelsson, Rozbeh Jafari et al. · Nature Communications · 2016 · 164 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Targeted NUDT5 inhibitors block hormone signaling in breast cancer cells

Brent D. G. Page, Nicholas C.K. Valerie, Roni H. G. Wright et al. · Nature Communications · 2018 · 124 citations · Full text

Medicine, Molecular Biology, Oncology +16

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

André Mateus, Laurie Gordon, Gareth Wayne et al. · Proceedings of the National Academy of Sciences · 2017 · 95 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +10

Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant <i>Mycobacterium tuberculosis</i>

Katharina Brunner, Selma Maric, Rudraraju Srilakshmi Reshma et al. · Journal of Medicinal Chemistry · 2016 · 66 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +15