Rozbeh Jafari

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

Daniel Martinez Molina, Rozbeh Jafari, Marina Ignatushchenko et al. · Science · 2013 · 2.2K citations

Medicine, Oncology, Pharmacology +17

The cellular thermal shift assay for evaluating drug target interactions in cells

Rozbeh Jafari, Helena Almqvist, Hanna Axelsson et al. · Nature Protocols · 2014 · 1.5K citations

Medicine, Cell Biology, Pharmacology +13

Tracking cancer drugs in living cells by thermal profiling of the proteome

Mikhail M. Savitski, Friedrich Reinhard, Holger Franken et al. · Science · 2014 · 1.2K citations

Pharmacy, Biochemistry, Oncology +17

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Helena Almqvist, Hanna Axelsson, Rozbeh Jafari et al. · Nature Communications · 2016 · 164 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Validation and development of MTH1 inhibitors for treatment of cancer

Ulrika Warpman Berglund, Kumar Sanjiv, Helge Gad et al. · Annals of Oncology · 2016 · 145 citations · Full text

Medicine, Oncology, Pharmacology +7