Concepedia

Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE

Stephen D. Miller, Carol L. Vanderlugt, Deborah J. Lenschow, Jonathan G. Pope, Nitin J. Karandikar, Mauro C. Dal Canto, Jeffrey A. Bluestone

Immunity · 1995 · 317 citations · 25 references

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25

CTLA-4 can function as a negative regulator of T cell activation

Theresa L. Walunas, Deborah J. Lenschow, Christina Y. Bakker et al. · Immunity · 1994 · 2.2K citations

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B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy

Vijay K. Kuchroo, Mercy Prabhu Das, Julia A. Brown et al. · Cell · 1995 · 1.7K citations · Full text

, , +15

Antigen presentation by chemically modified splenocytes induces antigen-specific T cell unresponsiveness in vitro and in vivo.

Marc K. Jenkins, R H Schwartz · The Journal of Experimental Medicine · 1987 · 1.2K citations · Full text

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Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

P S Linsley, William Brady, Laura S. Grosmaire et al. · The Journal of Experimental Medicine · 1991 · 1.1K citations · Full text

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Long-Term Survival of Xenogeneic Pancreatic Islet Grafts Induced by CTLA4lg

Deborah J. Lenschow, Yijun Zeng, J. Richard Thistlethwaite et al. · Science · 1992 · 1.1K citations

, , +17