Processing of Some Antigens by the Standard Proteasome but Not by the Immunoproteasome Results in Poor Presentation by Dendritic Cells

Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha.

Federica Sallusto, Antonio Lanzavecchia · The Journal of Experimental Medicine · 1994 · 5.2K citations · Full text

Life Sciences, Cell Biology, Immunology +17

Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells

Frank O. Nestlé, Selma Alijagic, Michel Gilliet et al. · Nature Medicine · 1998 · 2.9K citations

Medicine, Immunology, Oncology +14

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

Kenneth L. Rock, Colette F. Gramm, Lisa Rothstein et al. · Cell · 1994 · 2.5K citations

Life Sciences, Biochemistry, Immunology +14

Proliferating dendritic cell progenitors in human blood.

Nikolaus Romani, Susanne Grüner, D Brang et al. · The Journal of Experimental Medicine · 1994 · 1.9K citations · Full text

Life Sciences, Cell Biology, Hematology +9

Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma

Steven A. Rosenberg, James Chih‐Hsin Yang, Douglas J. Schwartzentruber et al. · Nature Medicine · 1998 · 1.8K citations

Medicine, Immunology, Oncology +16