AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity

Arnaud M. Didierlaurent, Sandra Morel, Laurence Lockman, +10

The Journal of Immunology

Adaptive Immune SystemInnate Immune SystemImmunologyImmunologic MechanismCd4 T Cell Responses +18

Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity

Sandra Morel, Arnaud M. Didierlaurent, Patricia Bourguignon, +7

Vaccine

InflammationAllergyAdjuvant System As03α-Tocopherol ModulatesAdaptive Immune System +9

Processing of Some Antigens by the Standard Proteasome but Not by the Immunoproteasome Results in Poor Presentation by Dendritic Cells

Sandra Morel, Frédéric Lévy, Odile Burlet‐Schiltz, +9

Immunity

Autoimmune DiseaseAllergyMedicineImmunologyProteasome +12

An Antigenic Peptide Produced by Peptide Splicing in the Proteasome

Nathalie Vigneron, Vincent Stroobant, Jacques Chapiro, +6

Science

Peptide EngineeringPeptide SplicingGlycobiologyProteasomeMolecular Biology +17

Enhancement of Adaptive Immunity by the Human Vaccine Adjuvant AS01 Depends on Activated Dendritic Cells

Arnaud M. Didierlaurent, Catherine Collignon, Patricia Bourguignon, +10

The Journal of Immunology

Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity

Margherita Coccia, Catherine Collignon, Caroline Hervé, +18

npj Vaccines

Destructive Cleavage of Antigenic Peptides Either by the Immunoproteasome or by the Standard Proteasome Results in Differential Antigen Presentation

Jacques Chapiro, Stéphane Claverol, Fanny Piette, +9

The Journal of Immunology

The Production of a New MAGE-3 Peptide Presented to Cytolytic T Lymphocytes by HLA-B40 Requires the Immunoproteasome

Erwin Schultz, Jacques Chapiro, Christophe Lurquin, +9

The Journal of Experimental Medicine

The Final N-Terminal Trimming of a Subaminoterminal Proline-Containing HLA Class I-Restricted Antigenic Peptide in the Cytosol Is Mediated by Two Peptidases

Frédéric Lévy, Lena Burri, Sandra Morel, +6

The Journal of Immunology

Processing of Tumor-Associated Antigen by the Proteasomes of Dendritic Cells Controls<i>In vivo</i>T-Cell Responses

Laurence Chapatte, Maha Ayyoub, Sandra Morel, +6

Cancer Research