Concepedia

Discovery of a new class of glucosylceramide synthase inhibitors

Elena S. Koltun, Steven J. Richards, Vicky Chan, Jason Nachtigall, Hongwang Du, Kevin Noson, Adam Galan, Naing Aay, Art Hanel, Amanda Harrison,

Bioorganic & Medicinal Chemistry Letters · 2011 · 14 citations · 12 references

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12

Ganglioside GM3 Participates in the Pathological Conditions of Insulin Resistance

Seiichi Tagami, Jin‐ichi Inokuchi, Kazuya Kabayama et al. · Journal of Biological Chemistry · 2002 · 350 citations · Full text

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Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity

Johannes M. F. G. Aerts, Roelof Ottenhoff, Andrew Powlson et al. · Diabetes · 2007 · 297 citations · Full text

, , +17

Inhibiting Glycosphingolipid Synthesis Improves Glycemic Control and Insulin Sensitivity in Animal Models of Type 2 Diabetes

Hongmei Zhao, Malgorzata Przybylska, I-Huan Wu et al. · Diabetes · 2007 · 239 citations · Full text

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A specific and potent inhibitor of glucosylceramide synthase for substrate inhibition therapy of Gaucher disease

Kerry Anne McEachern, John J. Fung, Svetlana Komarnitsky et al. · Molecular Genetics and Metabolism · 2007 · 178 citations

, , +11

Acetyl Chloride-Methanol as a Convenient Reagent for: A) Quantitative Formation of Amine Hydrochlorides B) Carboxylate Ester Formation C) Mild Removal of N-t-Boc-Protective Group.

Ayelet Nudelman, Yosi Bechor, Eliezer Falb et al. · Synthetic Communications · 1998 · 107 citations

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