Roelof Ottenhoff

Elevated globotriaosylsphingosine is a hallmark of Fabry disease

Johannes M. F. G. Aerts, J.E.M. Groener, Sijmen Kuiper et al. · Proceedings of the National Academy of Sciences · 2008 · 715 citations · Full text

Metabolic Syndrome, Fabry Disease, Lipid Storage +15

Pharmacological Inhibition of Glucosylceramide Synthase Enhances Insulin Sensitivity

Johannes M. F. G. Aerts, Roelof Ottenhoff, Andrew Powlson et al. · Diabetes · 2007 · 296 citations · Full text

Ultrasensitive in situ visualization of active glucocerebrosidase molecules

Martin D. Witte, Wouter W. Kallemeijn, Jan Aten et al. · Nature Chemical Biology · 2010 · 225 citations · Full text

Proteinlipid Interaction, Biochemistry, Bioanalysis +5

Hepatobiliary transport of glutathione and glutathione conjugate in rats with hereditary hyperbilirubinemia.

Ronald P.J. Oude Elferink, Roelof Ottenhoff, W. G. Liefting et al. · Journal of Clinical Investigation · 1989 · 170 citations · Full text

Lipid Peroxidation, Hereditary Hyperbilirubinemia, Oxidative Stress +18

Adenoviral overexpression of apolipoprotein A-V reduces serum levels of triglycerides and cholesterol in mice

Hendrik N. van der Vliet, Frank G. Schaap, J.H.M. Levels et al. · Biochemical and Biophysical Research Communications · 2002 · 168 citations

Inflammation, Metabolic Syndrome, Lipid Disorder +10