Publication | Closed Access
Acetyl Chloride-Methanol as a Convenient Reagent for: A) Quantitative Formation of Amine Hydrochlorides B) Carboxylate Ester Formation C) Mild Removal of N-t-Boc-Protective Group.
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Citations
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References
1998
Year
Mild RemovalChemical EngineeringEngineeringAbstract Hydrogen ChlorideMethanolAlcoholic SolutionsQuantitative FormationCatalytic SynthesisOrganic ChemistryConvenient ReagentCatalysisSynthetic ChemistryChemistryReagentPharmacologyDerivative (Chemistry)Useful ReagentBiomolecular Engineering
Abstract Hydrogen chloride qualitatively generated in situ by the addition of acetyl chloride to alcoholic solutions is a useful reagent for carboxylic acid esterification, N-t-Boc deprotection and phosphoramide solvolysis reactions.
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