Adam Galan

Discovery of selective, small-molecule inhibitors of RNA complexes—1. The tat protein/TAR RNA complexes required for HIV-1 transcription

Houng‐Yau Mei, David P. Mack, Adam Galan et al. · Bioorganic & Medicinal Chemistry · 1997 · 137 citations

Hiv-1 Transcription, Rna Complexes—1, Engineering +10

Inhibition of an HIV-1 Tat-derived peptide binding to TAR RNA by aminoglycoside antibiotics

Houng‐Yau Mei, Adam Galan, Nadia S. Halim et al. · Bioorganic & Medicinal Chemistry Letters · 1995 · 129 citations

Medicine, Human Retrovirus, Antiviral Drug Development +11

Discovery of XL413, a potent and selective CDC7 inhibitor

Elena S. Koltun, Amy Lew Tsuhako, David S. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 90 citations · Full text

Medicinal Chemistry, Drug Target, Selective Cdc7 Inhibitor +5

The design, synthesis, and biological evaluation of PIM kinase inhibitors

Amy Lew Tsuhako, David S. Brown, Elena S. Koltun et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 37 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Biochemistry +10

SAR and in vivo evaluation of 4-aryl-2-aminoalkylpyrimidines as potent and selective Janus kinase 2 (JAK2) inhibitors

Timothy P. Forsyth, Patrick C. Kearney, Byung Gyu Kim et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 34 citations · Full text

Medicinal Chemistry, Biochemistry, Vivo Evaluation +9