Concepedia

Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility

Robert M. Rzasa, Michael Frohn, Kristin L. Andrews, Samer Chmait, Ning Chen, Jeffrey Clarine, Carl D. Davis, Heather Eastwood, Daniel B. Horne, Essa Hu,

Bioorganic & Medicinal Chemistry · 2014 · 18 citations · 18 references

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18

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

Viktor Lakics, Eric Karran, Frank Boess · Neuropharmacology · 2010 · 464 citations

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Cloning and Characterization of a Novel Human Phosphodiesterase That Hydrolyzes Both cAMP and cGMP (PDE10A)

Kotomi Fujishige, Jun Kotera, Hideo Michibata et al. · Journal of Biological Chemistry · 1999 · 407 citations · Full text

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Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

Scott H. Soderling, Sharon J. Bayuga, Joseph A. Beavo · Proceedings of the National Academy of Sciences · 1999 · 381 citations

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Inhibition of the striatum-enriched phosphodiesterase PDE10A: A novel approach to the treatment of psychosis

Judith A. Siuciak, Douglas S. Chapin, John F. Harms et al. · Neuropharmacology · 2006 · 274 citations

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Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: Evidence for altered striatal function

Judith A. Siuciak, Sheryl A. McCarthy, Douglas S. Chapin et al. · Neuropharmacology · 2006 · 230 citations

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