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Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility

Medicinal ChemistryPreliminary Biological EvaluationBiochemistryMedicineNatural SciencesNovel Pde10a InhibitorsImproved SolubilityOrganic ChemistryPharmacotherapyDrug DevelopmentPharmacologyPharmaceutical ChemistryDrug Discovery