Heather Eastwood

Fragment Based Drug Discovery: Practical Implementation Based on ¹⁹F NMR Spectroscopy

John B. Jordan, Leszek Poppe, Xiaoyang Xia et al. · Journal of Medicinal Chemistry · 2011 · 81 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +9

Discovery and Optimization of Quinazolinone-pyrrolopyrrolones as Potent and Orally Bioavailable Pan-Pim Kinase Inhibitors

Liping H. Pettus, Kristin L. Andrews, Shon K. Booker et al. · Journal of Medicinal Chemistry · 2016 · 41 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +8

Discovery of (<i>R</i>)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4-<i>b</i>]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3<i>H</i>)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies

Hui-Ling Wang, Kristin L. Andrews, Shon K. Booker et al. · Journal of Medicinal Chemistry · 2019 · 27 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Disubstituted 1-Aryl-4-Aminopiperidine Library Synthesis Using Computational Drug Design and High-Throughput Batch and Flow Technologies

Marian C. Bryan, Christopher D. Hein, Hua Gao et al. · ACS Combinatorial Science · 2013 · 20 citations

Pharmacy, Medicinal Chemistry, Computational Chemistry +16

Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility

Robert M. Rzasa, Michael Frohn, Kristin L. Andrews et al. · Bioorganic & Medicinal Chemistry · 2014 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12