Analyzing Learned Molecular Representations for Property Prediction

Kevin Yang, Kyle Swanson, Wengong Jin, +12

Journal of Chemical Information and Modeling

Geometric LearningEngineeringMachine LearningComputational ChemistryGraph Processing +14

Chemi-Net: A Molecular Graph Convolutional Network for Accurate Drug Property Prediction

Ke Liu, Xiangyan Sun, Lei Jia, +7

International Journal of Molecular Sciences

Adapting ACMG/AMP sequence variant classification guidelines for single-gene copy number variants

Tracy Brandt, Laura M. Sack, Dolores Arjona, +13

Genetics in Medicine

Allelic VariantNext-generation SequencingGeneticsStatistical GeneticsGenome Analysis +7

Analyzing Learned Molecular Representations for Property Prediction

Kevin Yang, Kyle Swanson, Wengong Jin, +12

Geometric LearningEngineeringMachine LearningComputational ChemistryGraph Processing +14

Risk Factors, Clinical Features, and Outcomes of Recurrent Fungal Keratitis after Corneal Transplantation

Weiyun Shi, Ting Wang, Lixin Xie, +4

Ophthalmology

OphthalmologyCorneal DystrophyRecurrent Fungal KeratitisClinical FeaturesGlaucoma +5

Binary Quantitative Structure−Activity Relationship (QSAR) Analysis of Estrogen Receptor Ligands

Hua Gao, Chris Williams, Paul Labute, +1

Journal of Chemical Information and Computer Sciences

Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis

Shengqian Dou, Qun Wang, Bin Zhang, +10

Cell Discovery

Central CorneasCell LineageOcular DiseaseDevelopmental BiologyImplicated Mechanical Stretch +13

Immunostimulating Polysaccharides from Panax notoginseng

Hua Gao, Wang Feng-zhen, Eric J. Lien, +1

Pharmaceutical Research

Phenol toxicity in leukemia cells: a radical process?

Cynthia Dias Selassie, Tushini V. DeSoyza, Melissa C. del Rosario, +2

Chemico-Biological Interactions

Hematological MalignancyMixed-phenotype Acute LeukemiaCell DeathToxicologyMedicine +4

Discovery of PF-5190457, a Potent, Selective, and Orally Bioavailable Ghrelin Receptor Inverse Agonist Clinical Candidate

Samit K. Bhattacharya, Kim Andrews, Ramsay E. Beveridge, +25

ACS Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryBiochemistryG Protein-coupled ReceptorMedicine +8