Shon K. Booker

Discovery of a Covalent Inhibitor of KRAS^G12C (AMG 510) for the Treatment of Solid Tumors

Brian A. Lanman, Jennifer R. Allen, John G. Allen et al. · Journal of Medicinal Chemistry · 2019 · 677 citations · Full text

Drug Target, Solid Tumors, Molecular Biology +20

Discovery and Optimization of a Series of Benzothiazole Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors

Noel D. D’Angelo, Tae‐Seong Kim, Kristin L. Andrews et al. · Journal of Medicinal Chemistry · 2011 · 118 citations · Full text

Drug Target, Pharmacotherapy, Benzothiazole Phosphoinositide 3-Kinase +21

Design, Synthesis, and Biological Evaluation of Potent c-Met Inhibitors

Noel D. D’Angelo, Steven F. Bellon, Shon K. Booker et al. · Journal of Medicinal Chemistry · 2008 · 90 citations · Full text

Molecular Docking, Medicinal Chemistry, Drug Target +13

Discovery of 1<i>H</i>-Pyrazol-3(2<i>H</i>)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK)

Adrian L. Smith, Kristin L. Andrews, Holger Beckmann et al. · Journal of Medicinal Chemistry · 2015 · 80 citations · Full text

Drug Target, Selective Inhibitors, Molecular Pharmacology +17

Structure-Based Design of Novel Class II c-Met Inhibitors: 2. SAR and Kinase Selectivity Profiles of the Pyrazolone Series

Longbin Liu, Mark H. Norman, Matthew Lee et al. · Journal of Medicinal Chemistry · 2012 · 74 citations · Full text

Drug Target, Chemical Biology, Pharmaceutical Chemistry +21