Concepedia

AMPK binds to Sestrins and mediates the effect of exercise to increase insulin-sensitivity through autophagy

Xiaolei Liu, Yanmei Niu, Hairui Yuan, Jian Huang, Li Fu

Metabolism · 2015 · 114 citations · 26 references

DOI

Concepts

References

26

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 7K citations · Full text

, , +12

TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival

Ken Inoki, Tianqing Zhu, Kun‐Liang Guan · Cell · 2003 · 3.9K citations · Full text

, , +10

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Dana M. Gwinn, David B. Shackelford, Daniel F. Egan et al. · Molecular Cell · 2008 · 3.8K citations · Full text

, , +15

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Sung Hee Um, Francesca Frigerio, Mitsuhiro Watanabe et al. · Nature · 2004 · 1.7K citations · Full text

, , +14

p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling

Andrei V. Budanov, Michael Karin · Cell · 2008 · 1.3K citations · Full text

, , +14