Benoı̂t Viollet

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova et al. · Science · 2010 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +17

Metformin inhibits hepatic gluconeogenesis in mice independently of the LKB1/AMPK pathway via a decrease in hepatic energy state

Marc Foretz, Sophie Hébrard, Jocelyne Leclerc et al. · Journal of Clinical Investigation · 2010 · 1.2K citations · Full text

Life Sciences, Biochemistry, Physiology +17

Systemic Treatment with the Antidiabetic Drug Metformin Selectively Impairs p53-Deficient Tumor Cell Growth

Monica Buzzai, Russell G. Jones, Ravi K. Amaravadi et al. · Cancer Research · 2007 · 919 citations · Full text

Life Sciences, Oncology, Pharmacology +17

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

Brandon Faubert, Gino Boily, Said Izreig et al. · Cell Metabolism · 2012 · 911 citations · Full text

Life Sciences, Cancer Biology, Oncology +17