Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models

Li Fu, Kim K. Emmerton, Mechthild Jonas, +8

Cancer Research

ImmunologyImmunotherapyTumor BiologyPayload Influences PotencyBystander-killing Effects +14

mTOR and autophagy in normal brain aging and caloric restriction ameliorating age-related cognition deficits

Fengying Yang, Xiaolei Chu, Miaomiao Yin, +4

Behavioural Brain Research

Geriatric EndocrinologyNeuropsychologyCognitive ScienceAlzheimer's DiseaseAging +11

AMPK binds to Sestrins and mediates the effect of exercise to increase insulin-sensitivity through autophagy

Xiaolei Liu, Yanmei Niu, Hairui Yuan, +2

Metabolism

Metabolic SyndromeEnergy HomeostasisCell AutophagyMolecular PhysiologySignal Transduction +12

Bufalin stimulates antitumor immune response by driving tumor-infiltrating macrophage toward M1 phenotype in hepatocellular carcinoma

Zhuo Yu, Yuyao Li, Yue Li, +12

Journal for ImmunoTherapy of Cancer

Integrated genomic analysis identifies deregulated JAK/STAT-MYC-biosynthesis axis in aggressive NK-cell leukemia

Liang Huang, Dan Liu, Na Wang, +38

Cell Research

Jak/stat-myc-biosynthesis AxisHematological MalignancyFunctional GenomicsGenomic Analysis IdentifiesMixed-phenotype Acute Leukemia +8

Invasive Micropapillary Carcinoma of the Breast

Xiaojing Guo, Ling Chen, Ronggang Lang, +3

American Journal of Clinical Pathology

Breast OncologyAngiogenesisInvasive Micropapillary CarcinomaMedicineImmunology +10

Effect of exercise and butyrate supplementation on microbiota composition and lipid metabolism

Chunxia Yu, Sujuan Liu, Liqin Chen, +5

Journal of Endocrinology

Sestrin 2 induces autophagy and attenuates insulin resistance by regulating AMPK signaling in C2C12 myotubes

Huige Li, Sujuan Liu, Hairui Yuan, +2

Experimental Cell Research

Insulin ResistanceCell AutophagyMitophagyInsulin SignalingMolecular Physiology +13

Differences in semen quality, testicular histomorphology, fertility, reproductive hormone levels, and expression of candidate genes according to sperm motility in Beijing-You chickens

Yanyan Sun, Fuguang Xue, Yunlei Li, +5

Poultry Science

Testis WeightFertilityGeneticsGynecologySemen Analysis +17

ABHD5 blunts the sensitivity of colorectal cancer to fluorouracil via promoting autophagic uracil yield

Juanjuan Ou, Peng Yuan, Weiwen Yang, +15

Nature Communications