Effects of quercetin on the bioavailability of doxorubicin in rats: Role of CYP3A4 and P-gp inhibition by quercetin

Flavonoid Intake and Long-term Risk of Coronary Heart Disease and Cancer in the Seven Countries Study

Michaël G. L. Hertog · Archives of Internal Medicine · 1995 · 1.8K citations

Public Health, Nutrition, Nutritional Sciences +15

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

Carlos Cordon‐Cardo, James P. O’Brien, João Paulo Boccia et al. · Journal of Histochemistry & Cytochemistry · 1990 · 1.1K citations

Medicine, Molecular Biology, Oncology +14

Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism.

F. Peter Guengerich, M V Martin, Philippe Beaune et al. · Journal of Biological Chemistry · 1986 · 730 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Optimization of a quantitative HPLC determination of potentially anticarcinogenic flavonoids in vegetables and fruits

Michaël G. L. Hertog, P.C.H. Hollman, Dini P. Venema · Journal of Agricultural and Food Chemistry · 1992 · 711 citations

Agriculture, Food Science, Nutritional Sciences +12

Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition.

D. Ferry, Adam J. de Smith, J Malkhandi et al. · PubMed · 1996 · 630 citations

Medicine, Pharmacokinetics, Pharmacology +12