Adam J. de Smith

Phase I clinical trial of the flavonoid quercetin: pharmacokinetics and evidence for in vivo tyrosine kinase inhibition.

D. Ferry, Adam J. de Smith, J Malkhandi et al. · PubMed · 1996 · 630 citations

Molecular Pharmacology, Medicinal Chemistry, Urology +14

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2

Robin Walters, Sébastien Jacquemont, Armand Valsesia et al. · Nature · 2010 · 554 citations · Full text

Obesity, Metabolic Syndrome, Childhood Obesity +9

FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity

Manuela Fanciulli, Penny J. Norsworthy, Enrico Petretto et al. · Nature Genetics · 2007 · 462 citations · Full text

Immunogenetics, Autoimmune Disease, Autoantibody Production +9

A deletion of the HBII-85 class of small nucleolar RNAs (snoRNAs) is associated with hyperphagia, obesity and hypogonadism

Adam J. de Smith, Carolin Purmann, Robin Walters et al. · Human Molecular Genetics · 2009 · 352 citations · Full text

Novel Deletion, Metabolic Disorder, Genetics +19

Array CGH analysis of copy number variation identifies 1284 new genes variant in healthy white males: implications for association studies of complex diseases

Adam J. de Smith, Anya Tsalenko, Nick Sampas et al. · Human Molecular Genetics · 2007 · 212 citations